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KMID : 0383820080640030215
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Tuberculosis and Respiratory Diseases
2008 Volume.64 No. 3 p.215 ~ p.218
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Fatal Tumor Lysis Syndrome During Chemotherapy in Small Cell Lung Cancer
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Kook Eun-Hee
Kim Min-Soo
Ahn Se-Han
Jeon Se-Young
Yoon Jung-Ho
Han Min-Sung
Kim Cheol-Hyeon
Lee Jae-Chul
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Abstract
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Tumor lysis syndrome is a life-threatening complication of anti-cancer therapy that typically occurs in patients with large, rapidly growing and treatment-sensitive tumors such as high-grade lymphomas and acute leukemias. However, its incidence in solid tumors has been known to be very low. Tumor lysis syndrome in solid tumors has a high mortality rate owing to the lack of prophylactic therapy to prevent this complication. We report a case of fatal tumor lysis syndrome developed during chemotherapy in extensive-stage small cell lung cancer, along with a brief review of the relevant literature considering the rarity of this manifestation in solid tumor.
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KEYWORD
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Small cell Lung cancer, Tumor Lysis syndrome
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